Influenza A virus subtypes anf their pandemics
Flu Type of Virus Year Number of Deaths
Spanish [A (H1N1)] 1918-1919 50 million
Asian [A (H2N2)] 1957-1958 1 million
Hong Kong [A (H3N2)] 1968-1969 750.000
1957-58 and 1968-69 pandemics were result of Hong Kong flu [A (H3N2)] and Asian Flu [A (H2N2)] viruses have a combination of genes from a human influenza virus and an avian influenza virus. Also Spanish flu virus [A (H1N1)] has an avian origin. source Howard Hughes Medical Institute
Recombination between viruses
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